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Shanghai TheraMabs Bio-Technology Co.,Ltd


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Alirocumab
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Product: Views:381Alirocumab 
Unit price: Negotiable
MOQ:
Quantity:
Delivery date: Since the payment date Days delivery
Valid until: Long-term effective
Last updated: 2018-12-28 10:01
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Details

This product is the biosimilar of Alirocumab (1245916-14-6), which is a human monoclonal antibody that targets proprotein convertase subtilisin kexin type 9 (PCSK9). It is a PCSK9 inhibitor produced by recombinant DNA technology in Chinese Hamster Ovary cell suspension culture, which consists of two disulfide-linked human heavy chains, each covalently linked through a disulfide bond to a human kappa light chain. A single Nlinked glycosylation site is located in each heavy chain within the CH2 domain of the Fc constant region of the molecule. The variable domains of the heavy and light chains combine to form the PCSK9 binding site within the antibody. Molecular weight is approximate 146 kDa. 


Features and Advantages:

Name

Biosimilar of Alirocumab

CAS NO.

1245916-14-6

Type

Whole antibody

Source

Human

Target

PCSK9

Clone

Monoclone

Molecular Weight

146 kDa

Formula

C6472H9996N1736O2032S42

Antibody Form

Purified immunoglobulin

Physical Form

Solution

Place of Origin

China (Mainland)

Storage

Sealed and stored at -70±15℃, away from light


Specifications:

Our product is supplied at a concentration of 150 mg/mL in the same buffer system with original drug (PRALUENT). In addition, the concentration of the monoclonal antibody and the buffer formulation can be customized according to the customer's requirements.

Our company has four disposable bioreactors with an annual production capacity of 50~120kgs, Small samples (500mg~1g) are available for quality assessment, for more information please contact us.


Applications:

Alirocumab, sold under the trade name PRALUENT, used to treat high cholesterolfor adults whose cholesterol is not controlled by diet and statin treatment.

The production and filling of our company's monoclonal antibody products are in line with GMP production specifications as defined by the worldwide regulatory agencies. This product is only used for preclinical trials and can’t be used for clinical and commercial usage before approve by FDA.


http://www.therapeuticmab.com/

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